Copper-based detection allows detection recurrence early in patients with biochemical relapse. Since copper is present in higher levels in tumors, detection can occur with low PSAs.

From the ASCO Post

Highlights from the article include use of opioid medications for severe pain, dyspnea, suggestions for the treatment of neuropathic pain, and that depression is not a normal response to serious illness and SSRIs should be considered.

Over 50% major complication rate with high frailty in high-risk procedures. Association of Frailty With Failure to Rescue After Low- and High-Risk Inpatient Surgery

From: JAMA Surgery